GYNECOLOGIC MALIGNANCIES
Robert C. Bast Jr, MD
The University of Texas MD Anderson Cancer Center
Developed antibody that led to ovarian cancer biomarker
Acceptance Speech
- Robert C. Bast Jr, MD, is vice president for translational research, professor
of medicine, Department of Experimental Therapeutics, and the Harry
Carothers Wiess Distinguished University Chair for Cancer Research, The
University of Texas MD Anderson Cancer Center. His work and accomplishments
include:
- Developed the OC125 monoclonal antibody that led to the production of the CA125 radioimmunoassay, the first generally useful marker for monitoring the course of patients with epithelial ovarian cancer
- Research interests focus on cell growth regulation of ovarian and breast carcinomas, imprinted tumor suppressor genes, autophagy and tumor dormancy, early detection and prevention of ovarian cancer, and modulation of taxane sensitivity
- Recipient of numerous honors and awards, including the Shashikant Lele Lecture award from Roswell Park Cancer Institute in 2014, the Claudia Cohen Award from the Gynecological Cancer Foundation, and the Emil Frei, III Award for Excellence in Translational Research from MD Anderson Cancer Center in 2011
- Member of the American Association for Cancer Research and fellow of the American Association for the Advancement of Science
