Developed antibody that led to ovarian cancer biomarker
Acceptance Speech
Robert C. Bast Jr, MD, is vice president for translational research, professor
of medicine, Department of Experimental Therapeutics, and the Harry
Carothers Wiess Distinguished University Chair for Cancer Research, The
University of Texas MD Anderson Cancer Center. His work and accomplishments
include:
Developed the OC125 monoclonal antibody that led to the
production of the CA125 radioimmunoassay, the first generally
useful marker for monitoring the course of patients with epithelial
ovarian cancer
Research interests focus on cell growth regulation of ovarian and
breast carcinomas, imprinted tumor suppressor genes, autophagy
and tumor dormancy, early detection and prevention of ovarian
cancer, and modulation of taxane sensitivity
Recipient of numerous honors and awards, including the
Shashikant Lele Lecture award from Roswell Park Cancer Institute
in 2014, the Claudia Cohen Award from the Gynecological Cancer
Foundation, and the Emil Frei, III Award for Excellence in Translational
Research from MD Anderson Cancer Center in 2011
Member of the American Association for Cancer Research and
fellow of the American Association for the Advancement of Science